Publications

主な発表論文

〈最近の論文〉

Hui, S., Kimura, M., Kadowaki, Y., Tsuji, M., Inoue, M., Watanabe, N., and Yoshimura, K. Shear-induced ciliary autotomy mediated by a TRP channel and a voltage-dependent calcium channel. iScience 28: 113403, 2025. doi: 10.1016/j.isci.2025.113403.
Fueki, S., Kaneko, T., Matsuki, H., Hashimoto, Y., Yoshida, M., Isu, A., Wakabayashi, K.-I., and Yoshimura, K. Temperature-dependent augmentation of ciliary motility by the TRP2 channel in Chlamydomonas reinhardtii. Cytoskeleton 81: 578-585, 2024. doi: 10.1002/cm.21840
Oshima, D., Yoshida, M., Saga, K., Ito, N., Tsuji, M., Isu, A., Watanabe, N., Wakabayashi, K., and Yoshimura, K. Mechanoresponses mediated by the TRP11 channel in cilia of Chlamydomonas reinhardtii. iScience 26: 107926, 2023. doi: 10.1016/j.isci.2023.107926.
Tanno, A., Tokutsu, R., Arakaki, Y., Ueki, N., Minagawa, J., Yoshimura, K., Hisabori, T., Nozaki, H., and Wakabayashi, K. The four- celled Volvocales green alga Tetrabaena socialis exhibits weak photobehavior and high-photoprotection ability. PLoS ONE 16: e0259138, 2021. https://doi.org/10.1371/journal.pone.0259138
Yoshimura, K., Iida, K., and Iida, H. MCAs in Arabidopsis are Ca2+-permeable mechanosensitive channels inherently sensitive to membrane tension. Nat. Commun. 6074, 2021.
Yoshida, M., Yamamiya, R., Shimizu, Y. and Yoshimura, K. Transgenic Chlamydomonas expressing human transient receptor potential ankyrin 1 (TRPA1) channels to assess the effect of agonists and antagonists. Front. Pharmacol. 11: 578955. 2020. doi: 10.3389/fphar.2020.578955

〈これ以前の主要な論文〉

Owada, N., Yoshida, M., Morita, K., and Yoshimura, K. Temperature-sensitive Mutants of MscL Mechanosensitive Channel. J. Biochem. 166: 281-288, 2019.
Sekiguchi, M., Kameda, S., Kurosawa, S., Yoshida, M. and Yoshimura, K. Thermotaxis in Chlamydomonas is brought about by membrane excitation and controlled by redox conditions. Scientific Reports 8: 16114, 2018. 　
Saegusa, U. and Yoshimura K. cAMP controls the balance of the propulsive forces generated by the two flagella of Chlamydomonas. Cytoskeleton, 72: 412-421, 2015.
Ando C, Liu N, and Yoshimura K. A cytoplasmic helix is required for pentamer formation of the Escherichia coli MscL mechanosensitive channel. J. Biochem. 158: 109-114, 2015.
Nakayama, Y., Yoshimura, K. and Iida, H. Electrophysiological characterization of the mechanosensitive channel MscCG in Corynebacterium glutamicum. Biophys. J., 105: 1366-1375, 2013.
Nakayama, Y., Yoshimura, K. and Iida, H. Organellar mechanosensitive channels in fission yeast regulate the hypo-osmotic shock response. Nature Communications, 3: 1020, 2012.
Fujiu, K., Nakayama, Y. Iida, H., Sokabe, M. and Yoshimura, K. Mechanoreception in motile flagella of Chlamydomonas. Nature Cell Biology, 13: 630-632, 2011.
Fujiu, K., Nakayama, Y., Yanagisawa, A., Sokabe, M. and Yoshimura, K. Chlamydomonas CAV2 encodes a voltage-dependent calcium channel required for the flagellar waveform conversion. Current Biology, 19: 133-139, 2009.
Yoshimura, K., Usukura, J. and Sokabe, M. Gating associated conformational changes in the mechanosensitive channel MscL. Proc. Natl. Acad. Sci. U.S.A. 105: 4033-4038, 2008.
Nomura, T., Sokabe, M. and Yoshimura, K. Interaction between cytoplasmic and transmembrane domains of the mechanosensitive channel MscS. Biophys. J. 94: 1638-1645, 2008.
Nakayama, Y., Fujiu, K., Sokabe, M. and Yoshimura, K. Molecular and electrophysiological characterization of a mechanosensitive channel expressed in the chloroplasts of Chlamydomonas. Proc. Natl. Acad. Sci. U.S.A. 104: 5883-5888, 2007.
Okita, N., Isogai, N., Hirono, M., Kamiya, R. and Yoshimura, K. Phototactic activity in Chlamydomonas ‘non-phototactic’ mutants deficient in Ca2+-dependent control of flagellar dominance or in inner arm dynein. J. Cell Sci. 118: 529-537, 2005.
Yoshimura, K., Nomura, T. and Sokabe M. Loss-of-function mutations at the rim of the funnel of mechanosensitive channel MscL. Biophys. J. 86: 2113-2120, 2004.
Yoshimura, K., Matsuo, Y. and Kamiya, R. Gravitaxis in Chlamydomonas reinhardtii studied with novel mutants. Plant Cell Physiol. 44: 1112-1118, 2003.
Batiza, A. F., M-C. Kuo, Yoshimura, K. and Kung, C. Gating the bacterial mechanosensitive channel MscL in vivo. Proc. Natl. Acad. Sci. U.S.A. 99: 5643-5648, 2002.
Yoshimura, K., Batiza, A. and Kung, C. Chemically charging the pore constriction opens the mechanosensitive channel MscL. Biophys. J. 80: 2198-2206, 2001.
Yoshimura, K. and Kamiya, R. The sensitivity of Chlamydomonas photoreceptor is optimized for the frequency of cell body rotation. Plant Cell Physiol. 42: 665-672, 2001.
Isogai, N., Kamiya, R. and Yoshimura, K. Dominance between the two flagella during phototactic turning in Chlamydomonas. Zool. Sci. 17: 1261-1266, 2000.
Yoshimura, K., Batiza, A., Schroeder, M., Blount, P. and Kung, C. Hydrophilicity of a single residue within MscL correlates with increased channel mechanosensitivity. Biophys. J. 77: 1960-1972, 1999.
Matsuda, A., Yoshimura, K., Sineshchekov, O., Hirono, M. and Kamiya, R. Isolation and characterization of novel Chlamydomonas mutants that display phototaxis but not photophobic response. Cell Motil. Cytoskel. 41: 353-362, 1998.
Yoshimura, K. Mechanosensitive channels in the cell body of Chlamydomonas. J. Memb. Biol. 166: 149-155, 1998.
Bräucker, R., Murakami, A. Ikegaya, K., Yoshimura, K., Takahashi, K., Machemer-Rönisch, S. and Machemer, H. Relaxation and activation of graviresponses in Paramecium caudatum. J. Exp. Biol. 201: 2103-2113, 1998.
Yoshimura, K., Shingyoji, C. and Takahashi, K. Conversion of beating mode in Chlamydomonas flagella induced by electric stimulation. Cell Motil. Cytoskel. 36: 236-245, 1997.
Yoshimura, K. A novel type of mechanoreception by the flagella of Chlamydomonas. J. Exp. Biol. 199: 295-302, 1996.